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2012

Link TW; et al. Hyperglycemia is independently associated with post-operative function loss in patients with primary eloquent glioblastoma. J Clin Neurosci. 2012 May 15

Mathioudakis N.; et al. A Lifelong Smoker with Hypopituitarism: Rethinking the Hypothesis of a Tumor in the Hypophysis.Case Report Med. 2012

Garzon-Muvdi T.; et al. Regulation of Brain Tumor Dispersal by NKCC1 Through a Novel Role in Focal Adhesion Regulation. PLoS Biol. 2012 May;10

Katherine L.; et al. Insight Into Glaucoma Treatment in the Early 1900s Harvey Cushing's 1905 Operation. Arch Ophthalmol. 2012 Apr.

Chaichana KL.; et al. Seizure Control for Patients Undergoing Meningioma Surgery. World Neurosurg. 2012 Mar 30.

Chesler DA.; et al. The potential origin of glioblastoma initiating cells. Front Biosci (Schol Ed). 2012 Jan 1

Pendleton C.; et al. "Any possible restoration of function could not occur": Harvey Cushing and the early description of brain death.World Neurosurg. 2012 Feb

Pendleton C.; et al. "Glandular intoxication" following emergent tracheotomy during transsphenoidal surgery for acromegaly: Cushing's 1910 unrecognized case of thyroid storm? Pituitary. 2012 Jun

Pendleton C.; et al. "Can't walk nor raise arms to head": Harvey Cushing's surgical treatment of poliomyelitis. Spine (Phila Pa 1976). 2012 Feb.

Pendleton C.; et al. Harvey Cushing's contributions to motor mapping: 1902-1912. Cortex. 2012 Jan

Pendleton C.; et al. Early hypospadias repair: the contributions of Harvey Cushing. World J Urol. 2012 May.

2011

Pendleton C.; et al. Harvey Cushing's Approaches to Tumors in His Early Career: From the Skull Base to the Cranial Vault. Skull Base. 2011

Pendelton C.; et al. Transfacial approaches to the skull base: the early contributions of harvey cushing. Skull Base. 2011 Jul

Zamora-Berridi GJ.; et al. Santiago Ramón y Cajal and Harvey Cushing: two forefathers of neuroscience and neurosurgery.World Neurosurg. 2011 Nov.

Metha VA.; et al. Harvey Cushing and "birth hemorrhage": early pediatric neurosurgery at The Johns Hopkins Hospital.J Neurosurg Pediatr. 2011 Dec.

Pendleton C.; et al. Harvey Cushing's Early Treatment of Meningiomas: The Untold Story.World Neurosurg. 2011 Nov 7

Pendleton C.; et al. Early Multimodality Treatment of Intracranial Abscesses.World Neurosurg. 2011 Nov

Guerrero-Cázares H., et al. Glioblastoma Heterogeneity and More Accurate Representation in Research Models. World Neurosurg. 2011 Nov 1

Pendleton C.; et al. Sellar Door: Harvey Cushing's Entry into the Pituitary Gland, the Unabridged Johns Hopkins Experience 1896-1912.World Neurosurg. 2011 Nov 10

Dmetrichuk JM.; et al. Father of neurosurgery: Harvey Cushing's early experience with a pediatric brainstem glioma at the Johns Hopkins Hospital.J Neurosurg Pediatr. 2011 Oct.

Chan JY, et al. Endoscopic transvestibular paramandibular exploration of the infratemporal fossa and parapharyngeal space: a minimally invasive approach to the middle cranial base. Laryngoscope. 2011 Oct.

Zeng J.; et al. Nelfinavir induces radiation sensitization in pituitary adenoma cells. Cancer Biol Ther. 2011 Oct

Undabeita J.; et al. Operative treatment for microcephaly secondary to craniosynostosis at the turn of the twentieth century.Childs Nerv Syst. 2011 Nov

Chaichana KL., et al. The efficacy of carmustine wafers for older patients with glioblastoma multiforme: prolonging survival.Neurol Res. 2011 Sep

Pendleton C.; et al. Harvey Cushing: early use of tendon transfers for repair of foot deformity. A historical case report.Acta Orthop. 2011 Aug.

Zaidi HA.; et al. Harvey Cushing's repair of a dural defect after a traumatic brain injury: novel use of a fat graft.World Neurosurg. 2011 May-Jun

Hsu W.; et al. Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular target.J Neurosurg. 2011 Oct;

Latimer K.; et al. Dr. Harvey Cushing's attempts to cure migraine based on theories of pathophysiology.J Neurosurg. 2011 Nov

Pendleton C.; et al. Harvey Cushing and pediatric brain tumors at Johns Hopkins: the early stages of development.Harvey Cushing and pediatric brain tumors at Johns Hopkins: the early stages of development.J Neurosurg Pediatr. 2011 Jun

Li Y.; et al. c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype.Proc Natl Acad Sci U S A. 2011 Jun 14

Dmetrichuk JM.; et al. The understanding and operative treatment of cerebral palsy at the turn of the twentieth century: Harvey Cushing's early forays into pediatric neurosurgery. Childs Nerv Syst. 2011 Sep

Pendleton C.; et al. Unique challenges faced by pediatric neurosurgeon Harvey Cushing in 1909 at Johns Hopkins: a choroid plexus tumor of the lateral ventricle mimicking a cerebellar lesion. Childs Nerv Syst. 2011

Grossman R.; et al. Preoperative charlson comorbidity score predicts postoperative outcomes among older intracranial meningioma patients.World Neurosurg. 2011 Feb

Adams H.; et al. Harvey Cushing's case series of trigeminal neuralgia at the Johns Hopkins Hospital: a surgeon's quest to advance the treatment of the 'suicide disease'. Acta Neurochir (Wien). 2011 May.

Guerrero-Cázares H.; et al. Cytoarchitecture of the lateral ganglionic eminence and rostral extension of the lateral ventricle in the human fetal brain.J Comp Neurol. 2011 Apr 15

Latimer K.; et al. Harvey Cushing's open and thorough documentation of surgical mishaps at the dawn of neurologic surgery. Arch Surg. 2011 Feb

Redmond KJ.; et al. A radiotherapy technique to limit dose to neural progenitor cell niches without compromising tumor coverage. J Neurooncol. 2011 Sep

Kim T.; et al. Mesoporous silica-coated hollow manganese oxide nanoparticles as positive T1 contrast agents for labeling and MRI tracking of adipose-derived mesenchymal stem cells. J Am Chem Soc. 2011 Mar 9

Zaidi HA.; et al. Harvey Cushing's innovative attempt at xenotransplanting a rabbit spinal cord in a patient after resection of a peripheral nerve tumor in 1902. Neurosurgery. 2011 Mar

Sedora-Román NI.; et al. Harvey Cushing's early experience with pediatric gliomas. Childs Nerv Syst. 2011 May

Krüppel-like family of transcription factor 9, a differentiation-associated transcription factor, suppresses Notch1 signaling and inhibits glioblastoma-initiating stem cells. Stem Cells. 2011 Jan. Ying M.

Dasenbrock HH; et al. "Fulfilling the chief of his duties as a physician": Harvey Cushing, selective dorsal rhizotomy and elective spine surgery for quality of life. J Neurosurg Spine. 2011 Mar.

Dasenbrok HH; et al. "No performance in surgery more interesting and satisfactory": Harvey Cushing and his experience with spinal cord tumors at the Johns Hopkins Hospital. J Neurosurg Spine. 2011 Mar.

Bydon A.; et al. Harvey Cushing, the spine surgeon: the surgical treatment of Pott disease. Spine (Phila Pa 1976). 2011 Aug

Pendleton C.; et al. Harvey Cushing and early spinal dysraphism repair at Johns Hopkins Hospital. J Neurosurg Pediatr. 2011 Jan

Dasenbrock HH.; et al. "No clinical puzzles more interesting": Harvey Cushing and spinal trauma, the Johns Hopkins Hospital 1896-1912. Neurosurgery. 2011 Feb

Pendleton C.; et al. "Groans less, seems more comfortable:" Harvey Cushing's redefinition of success in the operative treatment of pediatric intracranial lesions. Childs Nerv Syst. 2011 Jan.

Chaichana KL.; et al. Surgical outcomes for older patients with glioblastoma multiforme: preoperative factors associated with decreased survival. Clinical article. J Neurosurg. 2011 Mar

Menucci M.; et al. Effect of dopaminergic drug treatment on surgical findings in prolactinomas. Pituitary. 2011 Mar

Raza SM.; et al. The extended retrosigmoid approach for neoplastic lesions in the posterior fossa: technique modification. Neurosurg Rev. 2011 Jan.

Pendleton C.; et al. On the shoulders of giants: Harvey Cushing's experience with acromegaly and gigantism at the Johns Hopkins Hospital, 1896-1912. Pituitary. 2011 Mar

Chaichana KL.; et al. Supratentorial glioblastoma multiforme: the role of surgical resection versus biopsy among older patients. Ann Surg Oncol. 2011 Jan

Chaichana KL; et al. Factors involved in maintaining prolonged functional independence following supratentorial glioblastoma resection. Clinical article. J Neurosurg. 2011 Mar

2010

Pendleton C.; et al. Harvey Cushing's surgical treatment of a pediatric patient with an intraventricular glioma.Pediatr Neurosurg. 2010

Tzeng SY.; et al. Non-viral gene delivery nanoparticles based on poly(β-amino esters) for treatment of glioblastoma.Biomaterials. 2011 Aug.

Pendleton C. "Glandular intoxication" following emergent tracheotomy during transsphenoidal surgery for acromegaly: Cushing's 1910 unrecognized case of thyroid storm? Pituitary. 2012 Jun.

Owusu Boahene KD; et al. transpalpebral orbitofrontal craniotomy: a minimally invasive approach to anterior cranial vault lesions. Skull Base. 2010 Jul.

Gonzalez-Perez O.; et al. Targeting of deep brain structures with microinjections for delivery of drugs, viral vectors, or cell transplants. J Vis Exp. 2010 Dec

Raza SM.; et al. The transpalpebral incision: its use in keyhole approaches to cranial base brain tumors. Expert Rev Neurother. 2010

Dorafshar AH.; et al. Cleft lip-cleft palate closure: the unknown contributions of Harvey Cushing.Plast Reconstr Surg. 2010 Oct.

Kellogg R.; et al. Surgical treatment of trigeminal neuralgia: a history of early strides toward curing a "cancerous acrimony". Neurosurgery. 2010 Nov.

Gonzalez-Perez O.; et al. Immunological control of adult neural stem cells. J Stem Cells. 2010.

Sun DQ.; et al. Treatment of pituitary adenomas using radiosurgery and radiotherapy: a single center experience and review of literature. Neurosurg Rev. 2010

Grossman R.; et al. Predictors of inpatient death and complications among postoperative elderly patients with metastatic brain tumors. Ann Surg Oncol. 2011 Feb

Pendleton C.; et al. The elusive Minnie G.: revisiting Cushing's case XLV, and his early attempts at improving quality of life. Pituitary. 2010 Dec.

Mohyeldin A. Oxygen in stem cell biology: a critical component of the stem cell niche. Cell Stem Cell. 2010 Aug

Conway JE.; et al. A surgical modification for performing orbitozygomatic osteotomies: technical note. Neurosurg Rev. 2010 Oct

de Almeida JP.; et al. Pituitary stem cells: review of the literature and current understanding. Neurosurgery. 2010 Sep.

Momin EN.; et al. The Oncogenic Potential of Mesenchymal Stem Cells in the Treatment of Cancer: Directions for Future Research. Curr Immunol Rev. 2010 May

Grossman R.; et al. Complications and death among elderly patients undergoing pituitary tumour surgery. Clin Endocrinol (Oxf). 2010 Sep

Frazier JL.; et al. Rapid malignant transformation of low-grade astrocytomas: report of 2 cases and review of the literature.World Neurosurg. 2010 Jan.

Pendleton C.; et al. Harvey Cushing's use of a transplanted human vein to treat hydrocephalus in an infant in the early 1900s. Historical vignette. J Neurosurg Pediatr. 2010 May

Chaicana KL.; et al. Prognostic significance of contrast-enhancing anaplastic astrocytomas in adults. J Neurosurg. 2010 Aug.

Mukherjee D.; et al. Disparities in access to neuro-oncologic care in the United States. Arch Surg. 2010 Mar.

Vogel TD.; et al. Surgery for cervical dystonia: the emergence of denervation and myotomy techniques and the contributions of early surgeons at The Johns Hopkins Hospital. J Neurosurg Spine. 2010 Mar

Gonzalez-Perez O.; et al. Dose-dependent effect of EGF on migration and differentiation of adult subventricular zone astrocytes. Glia. 2010 Jun

Achanta P.; et al. Gliomagenesis and the use of neural stem cells in brain tumor treatment. Anticancer Agents Med Chem. 2010 Feb.

Mukherjee D.; et al. Giant encephalocele. Br J Neurosurg. 2010 Apr

Hales RK.; et al. Prognostic factors in pediatric high-grade astrocytoma: the importance of accurate pathologic diagnosis. J Neurooncol. 2010 Aug.

Pendleton C.; et al. Harvey Cushing's attempt at the first human pituitary transplantation. Nat Rev Endocrinol. 2010 Jan.

Baird CJ.; et al. Radiographic and anatomic basis of endoscopic anterior craniocervical decompression: a comparison of endonasal, transoral, and transcervical approaches. Neurosurgery. 2009 Dec.

Mukherjee D; et al. Variations in referral patterns for hypophysectomies among pediatric patients with sellar and parasellar tumors. Childs Nerv Syst. 2010 Mar

Chaichana K.; et al. A proposed classification system that projects outcomes based on preoperative variables for adult patients with glioblastoma multiforme. J Neurosurg. 2010 May

Raza SM.; et al. A modified frontal-nasal-orbital approach to midline lesions of the anterior cranial fossa and skull base: technical note with case illustrations.Neurosurg Rev. 2010 Jan

Mukherjee D.; et al. New methods to assess trends in neuro-oncological care. J Neurooncol. 2010 Mar.

Chaichana KL.; et al. Persistent outpatient hyperglycemia is independently associated with survival, recurrence and malignant degeneration following surgery for hemispheric low grade gliomas. Neurol Res. 2010 May.

Chaichana KL.; et al. Recurrence and malignant degeneration after resection of adult hemispheric low-grade gliomas. J Neurosurg. 2010 Jan

2009

Garzón-Muvdi T.; et al. Neural stem cell niches and homing: recruitment and integration into functional tissues. ILAR J. 2009

Purger D.; et al. A histology-based atlas of the C57BL/6J mouse brain deformably registered to in vivo MRI for localized radiation and surgical targeting. Phys Med Biol. 2009 Dec .

Quiñones-Hinojosa A.; et al. Pre-operative factors affecting resectability of giant intracranial meningiomas.Can J Neurol Sci. 2009 Sep.

Patel NB.; et al. A unique experiment in neurological surgery: intracerebral injection of antitoxin for tetanus.J Neurosurg. 2010 Jun.

Mukherjee D.; et al. Disparities in access to pediatric neurooncological surgery in the United States. Pediatrics. 2009 Oct

McGirt MJ.; et al. Association of surgically acquired motor and language deficits on overall survival after resection of glioblastoma multiforme. Neurosurgery. 2009 Sep.

Guerrero-Cázares H.; et al. Neurosphere culture and human organotypic model to evaluate brain tumor stem cells. Methods Mol Biol. 2009.

Rodríguez D.; et al. Outcomes of malignant CNS ependymomas: an examination of 2408 cases through the Surveillance, Epidemiology, and End Results (SEER) database (1973-2005).J Surg Res. 2009 Oct.

Sun P.; et al. DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere cell differentiation and tumor propagation. Stem Cells. 2009 Jul;27

Mukherjee D.; et al. Predictors of access to pituitary tumor resection in the United States, 1988-2005. Eur J Endocrinol. 2009 Aug.

Kosztowski T.; et al. Applications of neural and mesenchymal stem cells in the treatment of gliomas. Expert Rev Anticancer Ther. 2009 May.

Zaidi HA.; et al. Origins and clinical implications of the brain tumor stem cell hypothesis. J Neurooncol. 2009 Ma.

Chaichana KL.; et al. Intra-operatively obtained human tissue: protocols and techniques for the study of neural stem cells.J Neurosci Methods.

Chaichana KL.; et al. Long-term seizure outcomes in adult patients undergoing primary resection of malignant brain astrocytomas. Clinical article. J Neurosurg. 2009 Aug

Quiñones-Hinojosa A.; et al. Surgical considerations in the management of falcotentorial meningiomas: advantages of the bilateral occipital transtentorial/transfalcine craniotomy for large tumors. Neurosurgery. 2009 May.

Frazier JL.; et al. Isolated Whipple disease of the brain resembling a tumour. Acta Neurochir (Wien). 2009 Feb.

McGirt MJ.; et al. Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme. J Neurosurg. 2009 Mar.

Gathinji M.; et al. Association of preoperative depression and survival after resection of malignant brain astrocytoma. Surg Neurol. 2009 Mar.

2008

McGirt MJ.; et al. Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas. Neurosurgery 2008 Oct.

McGirt MJ.; et al. Persistent outpatient hyperglycemia is independently associated with decreased survival after primary resection of malignant brain astrocytomas. Neurosurgery. 2008 Aug.

Frazier JL.; et al. Combined endoscopic and microscopic management of pediatric pituitary region tumors through one nostril: technical note with case illustrations. Childs Nerv Syst. 2008 Dec.

Attenello FJ.; et al. Use of Gliadel (BCNU) wafer in the surgical treatment of malignant glioma: a 10-year institutional experience.Ann Surg Oncol. 2008 Oct

Niazi T.; et al. Management of brain abscesses associated with halo fixation. Neurosurg Focus. 2008

Chaichana KL.; et al. Relationship of glioblastoma multiforme to the lateral ventricles predicts survival following tumor resection. J Neurooncol. 2008 Sep.

Chang EF.; et al. Long-term recurrence and mortality after surgery and adjuvant radiotherapy for nonfunctional pituitary adenomas. J Neurosurg. 2008 Apr.

Sanai N. Safety and efficacy of the direct endonasal transsphenoidal approach for challenging sellar tumors. J Neurooncol. 2008 May.

2007

Quiñones-Hinojosa A. Terra firma--a journey from migrant farm labor to neurosurgery. N Engl J Med. 2007 Aug 9

Chaichana KL.; et al. Preservation of glial cytoarchitecture from ex vivo human tumor and non-tumor cerebral cortical explants: A human model to study neurological diseases. J Neurosci Methods. 2007 Aug.

2006

Chaichana K.; et al. Neurosphere assays: growth factors and hormone differences in tumor and nontumor studies. Stem Cells. 2006 Dec.

Smith JS.; et al. Limitations of diffusion-weighted imaging in distinguishing between a brain tumor and a central nervous system histoplasmoma. J Neurooncol. 2006 Sep

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Alfredo Quiñones-Hinojosa
Johns Hopkins Bayview Medical Center
301 Mason Lord Drive / 2nd Floor
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Email: drq@jhmi.edu

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